No theory of undirected chemical evolution has explained the origin of the information in DNA (or RNA) needed to build the first living cell from simpler non-living chemicals. Instead, our uniform and repeated experience — the basis of all scientific reasoning — shows that systems possessing functional or digital information invariably arise from intelligent causes. We know from experience that software comes from programmers. We know generally that information — whether inscribed in hieroglyphics, written in a book, or encoded in radio signals — always arises from an intelligent source. So the discovery of information — and a complex information transmission and processing system — in every living cell, provides strong grounds for inferring that intelligence played a role in life’s origin. As information theorist Henry Quastler observed, “information habitually arises from conscious activity.” Historian of science Fredrick Burnham notes: “the idea that God created the universe [is] a more respectable hypothesis today than at any time in the last 100 years.” In my book Return of the God Hypothesis, I concur, and argue that recent scientific discoveries about biological and cosmological origins have decidedly theistic implications, suggesting that popular scientific reports of the death of God may have been — to adapt Mark Twain’s famous quip — greatly exaggerated.