In a Dec. 14 press release and in letters to leaders at the Department of Health and Human Services (HHS), the FDA and the National Institute of Allergy and Infectious Diseases (NIAID), CHD warned about PEG’s known association with adverse immune responses, including life-threatening anaphylaxis. An estimated 72% of the general population has anti-PEG antibodies (including elevated levels in 8% of Americans) that can set those individuals up for adverse reactions when later exposed to PEG-containing substances. Pharmaceutical and biotech companies, acutely aware of the correlation between anti-drug antibodies and increased adverse effects, acknowledge that the phenomenon poses a “vexing” and “serious” clinical problem — one that has come into sharp relief as recipients of COVID mRNA injections experience severe allergic reactions.
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